In a match played at Ghana's home ground, counting towards the first round of Group F, the only goal was scored by Milson, in the 90+3 minute, in a match in which the hosts demonstrated slight superiority throughout the 90 minutes.
The Angolans, with three points, share the lead in Group F with Sudan, who beat Niger 1-0 on Wednesday.
The national team will play again next Monday, in Luanda, when they host Sudan, in the second round of the tournament.
The biggest African football tournament will be held from 21 December 2025 to 18 January 2026, in Morocco.