In a statement released on Thursday, the carrier indicated that among the eliminated international routes are the Angolan capital, Luanda, and the Brazilian city of São Paulo.
Among the international flights the company has decided to keep is the route to the capital of Mozambique, Maputo.
SAA will also abandon connections to the Chinese city of Guangzhou (Guangzhou) and the Chinese special administrative region of Hong Kong, at a time when several airlines have suspended flights to mainland China due to the coronavirus outbreak.
The South African carrier stressed that all passengers with tickets for flights canceled from 1 March will receive a full refund.
The airline's bankruptcy managers stressed that the measures are part of a restructuring plan that will be released in late February.
SAA had already announced the cancellation of around 150 flights scheduled for February to cut costs.
The company, which has suffered losses since 2011, employs around ten thousand people, in a country that has an unemployment rate of 29 percent.
In late January, the Development Bank of South Africa, a state-owned institution, announced a loan of 3.5 billion rand (about 230 million dollars) to the company, eliminating the risk of bankruptcy.