According to the Angolan Football Federation (FAF), Ricardo Batista cited family reasons for asking to be released from the 'Palancas Negras', having been replaced by Agostinho Kalunga, from Wiliete de Benguela.
Clinton da Mata was dismissed due to physical problems, according to the FAF.
With 12 points gained in the first four rounds of Group F, Angola has already secured its 10th presence in CAN2025.
The team led by Portuguese Pedro Gonçalves hosts Ghana, third with two points, on Friday, in Luanda, and faces Sudan, three days later, in Benghazi, Libya.
CAN2025 will be held in Morocco, between December 21, 2025 and January 18, 2026.